Mus musculus Protein: Crot
Summary
InnateDB Protein IDBP-134509.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Crot
Protein Name carnitine O-octanoyltransferase
Synonyms 1200003H03Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000003720
InnateDB Gene IDBG-134507 (Crot)
Protein Structure
UniProt Annotation
Function Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. {ECO:0000269PubMed:15492013}.
Subcellular Localization Peroxisome {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0008458 carnitine O-octanoyltransferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0006631 fatty acid metabolic process
GO:0006635 fatty acid beta-oxidation
GO:0009437 carnitine metabolic process
GO:0015908 fatty acid transport
GO:0015936 coenzyme A metabolic process
GO:0051791 medium-chain fatty acid metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005777 peroxisome
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID MGI:1921364
InterPro IPR000542 Acyltransferase ChoActase/COT/CPT
PFAM PF00755
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DC50
PhosphoSite PhosphoSite-Q9DC50
TrEMBL Q9QZZ3
UniProt Splice Variant
Entrez Gene 74114
UniGene Mm.28197
RefSeq NP_076222
MGI ID 1XMD
MGI Symbol Crot
OMIM
CCDS CCDS19087
HPRD
IMGT
EMBL AF144397 AK004567 BC006593 BC012308
GenPept AAD55365 AAH06593 AAH12308 BAB23378