Version 5.4
Homo sapiens Protein: MIOX
Summary
InnateDB Protein IDBP-13544.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MIOX
Protein Name myo-inositol oxygenase
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000216075
InnateDB Gene IDBG-13542 (MIOX)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Kidney specific.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004033 aldo-keto reductase (NADP) activity
GO:0005506 iron ion binding
GO:0008199 ferric iron binding
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
GO:0050113 inositol oxygenase activity
GO:0050661 NADP binding
Biological Process
GO:0019310 inositol catabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0016234 inclusion body
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR007828 Inositol oxygenase
PFAM PF05153
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UGB7
PhosphoSite PhosphoSite-Q9UGB7
TrEMBL
UniProt Splice Variant
Entrez Gene 55586
UniGene Hs.129227
RefSeq NP_060054
HUGO HGNC:14522
OMIM 606774
CCDS CCDS14092
HPRD 12443
IMGT
EMBL AF197129 AF230095 AK000576 AL096767 AY064416 AY738258 BC012025 BC073848 CH471138 CR456478
GenPept AAF25204 AAH12025 AAH73848 AAK00766 AAL47192 AAV65816 BAA91266 CAB63064 CAG30364 CAO03465 EAW73547

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca