Version 5.4
Mus musculus Protein: Mpc1
Summary
InnateDB Protein IDBP-135548.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mpc1
Protein Name brain protein 44-like
Synonyms 0610006G08Rik; 3830411I18Rik; Brp44l;
Species Mus musculus
Ensembl Protein ENSMUSP00000045654
InnateDB Gene IDBG-135546 (Mpc1)
Protein Structure
UniProt Annotation
Function Mediates the uptake of pyruvate into mitochondria. {ECO:0000269PubMed:22628554}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000269PubMed:22628554}; Multi-pass membrane protein {ECO:0000269PubMed:22628554}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0050833 pyruvate transmembrane transporter activity
Biological Process
GO:0006090 pyruvate metabolic process
GO:0006850 mitochondrial pyruvate transport
GO:1901475 pyruvate transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1915240
InterPro IPR005336 Mitochondrial pyruvate carrier
PFAM PF03650
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P63030
PhosphoSite PhosphoSite-P63030
TrEMBL Q3UX28
UniProt Splice Variant
Entrez Gene 55951
UniGene
RefSeq
MGI ID
MGI Symbol Mpc1
OMIM
CCDS
HPRD
IMGT
EMBL AC164431 AF181116 AK002241 AK002266 AK004013 AK013391 AK014421 AK135943 BC024365 BC103767 CH466619
GenPept AAF25816 AAH24365 AAI03768 BAB21958 BAB21976 BAB23124 BAB28826 BAB29340 BAE22735 EDL02122 EDL02123

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca