Version 5.4
Mus musculus Protein: Etl4
Summary
InnateDB Protein IDBP-140424.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Etl4
Protein Name enhancer trap locus 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000041431
InnateDB Gene IDBG-140422 (Etl4)
Protein Structure
UniProt Annotation
Function Required for normal development of intervertebral disks. {ECO:0000269PubMed:16204209}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:16204209}.
Disease Associations
Tissue Specificity Expressed predominantly in the notochord and mesonephros during embryogenesis as well as in other areas such as the epithalamus sulcus, lens vesicle, inner retinal layer, heart, hepatic primordial surface, infundibulum, surface ectoderm, hind gut and limb bud mesenchyme. In adults, expressed in a range of tissues including the nucleus pulposus, corpus callosum, kidney, cardiac muscle, Sertoli cells and hair follicles. {ECO:0000269PubMed:16204209}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0048706 embryonic skeletal system development
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:95454
InterPro IPR022782 Actin interacting protein 3, C-terminal
PFAM PF03915
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2AQ25
PhosphoSite PhosphoSite-BAC41473
TrEMBL Q3UFL8
UniProt Splice Variant
Entrez Gene 208618
UniGene Mm.397986
RefSeq NP_835160
MGI ID
MGI Symbol Etl4
OMIM
CCDS CCDS50511
HPRD
IMGT
EMBL AB093289 AB125594 AB125595 AK052733 AK054453 AK148418 AL844538 AL929100 BC026657 BC050016
GenPept AAH26657 AAH50016 BAC35121 BAC35783 BAC41473 BAD14929 BAD14930 BAE28542 CAM19813 CAM19814 CAM19815 CAM24302 CAM24303 CAM24304 CAM24306 CAM24307 CAM24308

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca