Version 5.4
Homo sapiens Protein: ARSA
Summary
InnateDB Protein IDBP-14146.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARSA
Protein Name arylsulfatase A
Synonyms MLD;
Species Homo sapiens
Ensembl Protein ENSP00000348406
InnateDB Gene IDBG-14144 (ARSA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004098 cerebroside-sulfatase activity
GO:0005509 calcium ion binding
GO:0008484 sulfuric ester hydrolase activity
Biological Process
GO:0006665 sphingolipid metabolic process
GO:0006687 glycosphingolipid metabolic process
GO:0008152 metabolic process
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005764 lysosome
GO:0005788 endoplasmic reticulum lumen
GO:0043202 lysosomal lumen
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000917 Sulfatase
IPR017850 Alkaline-phosphatase-like, core domain
PFAM PF00884
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P15289
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 410
UniGene Hs.88251
RefSeq NP_001078895
HUGO HGNC:713
OMIM 607574
CCDS CCDS14100
HPRD 09617
IMGT
EMBL AB448736 AK098659 AK315011 AY271820 BC014210 CR456383 U62317 X52150 X52151
GenPept AAB03341 AAH14210 AAP03431 BAG37503 BAH11167 CAA36398 CAA36399 CAG30269

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca