Version 5.4
Mus musculus Protein: Fbxo33
Summary
InnateDB Protein IDBP-142493.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbxo33
Protein Name F-box protein 33
Synonyms 5730501N20Rik; AI642135;
Species Mus musculus
Ensembl Protein ENSMUSP00000035948
InnateDB Gene IDBG-142491 (Fbxo33)
Protein Structure
UniProt Annotation
Function Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1. {ECO:0000269PubMed:16797541}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1917861
InterPro IPR001810 F-box domain
PFAM PF00646
PF12937
PF13013
PRINTS
PIRSF
SMART SM00256
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VE08
PhosphoSite PhosphoSite-
TrEMBL Q3V1V2
UniProt Splice Variant
Entrez Gene 70611
UniGene Mm.490757
RefSeq NP_001028328
MGI ID
MGI Symbol Fbxo33
OMIM
CCDS CCDS49072
HPRD
IMGT
EMBL AC147101 AK132233 BC006669 BC020022 BC138618 BC138621
GenPept AAH06669 AAH20022 AAI38619 AAI38622 BAE21047

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca