Version 5.4
Mus musculus Protein: Nf2
Summary
InnateDB Protein IDBP-143000.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nf2
Protein Name neurofibromatosis 2
Synonyms merlin;
Species Mus musculus
Ensembl Protein ENSMUSP00000091066
InnateDB Gene IDBG-142996 (Nf2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 36 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0008092 cytoskeletal protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0019898 extrinsic component of membrane
Protein Structure and Domains
PDB ID MGI:97307
InterPro IPR000299 FERM domain
IPR000533 Tropomyosin
IPR000798 Ezrin/radixin/moesin like
IPR008954 Moesin tail domain
IPR011174 Ezrin/radixin/moesin
IPR011259 Ezrin/radixin/moesin, C-terminal
IPR018980 FERM, C-terminal PH-like domain
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR019750 Band 4.1 family
IPR029071 Ubiquitin-related domain
PFAM PF00261
PF12718
PF00769
PF09380
PF00373
PRINTS PR00194
PR00661
PR00935
PIRSF PIRSF002305
SMART SM00295
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 18016
UniGene
RefSeq NP_001239182
MGI ID
MGI Symbol Nf2
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca