Version 5.4
Mus musculus Protein: Gtf3c6
Summary
InnateDB Protein IDBP-145320.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gtf3c6
Protein Name general transcription factor IIIC, polypeptide 6, alpha
Synonyms 2410016F19Rik; AU019813;
Species Mus musculus
Ensembl Protein ENSMUSP00000019982
InnateDB Gene IDBG-145318 (Gtf3c6)
Protein Structure
UniProt Annotation
Function Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters (By similarity). {ECO:0000250UniProtKB:Q969F1}.
Subcellular Localization Nucleus {ECO:0000250UniProtKB:Q969F1}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006383 transcription from RNA polymerase III promoter
Cellular Component
GO:0000127 transcription factor TFIIIC complex
Protein Structure and Domains
PDB ID MGI:1914621
InterPro IPR019481 Transcription factor TFIIIC, tau55-related
PFAM PF10419
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D8P7
PhosphoSite PhosphoSite-Q9D8P7
TrEMBL Q9DB36
UniProt Splice Variant
Entrez Gene 67371
UniGene Mm.64104
RefSeq NP_080389
MGI ID
MGI Symbol Gtf3c6
OMIM
CCDS CCDS23794
HPRD
IMGT
EMBL AK005261 AK007816 AK162053 AK168070 BC027260 BC048446
GenPept AAH27260 AAH48446 BAB23913 BAB25281 BAE36699 BAE40045

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca