InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cdc40

Summary

InnateDB Protein

IDBP-146004.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cdc40

Protein Name

cell division cycle 40 homolog (yeast)

Synonyms

1200003H23Rik; EHB3; PRP17;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000044305

InnateDB Gene

IDBG-146000 (Cdc40)

Protein Structure

UniProt Annotation

Function

Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006397	mRNA processing
GO:0008380	RNA splicing

Cellular Component

GO:0071013

catalytic step 2 spliceosome

Protein Structure and Domains

PDB ID

MGI:1918963

InterPro

IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain

PFAM

PF00400

PRINTS

PIRSF

SMART

SM00320

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9DC48

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

71713

UniGene

Mm.46063

RefSeq

NP_082155

MGI ID

MGI Symbol

Cdc40

OMIM

CCDS

CCDS48546

HPRD

IMGT

EMBL

AK004569 BC147503 BC158078

GenPept

AAI47504 AAI58079 BAB23380