InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cd164

Summary

InnateDB Protein

IDBP-146849.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cd164

Protein Name

CD164 antigen

Synonyms

A115; A24; AA589639; AW540279; MGC-24; MSSP;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000019962

InnateDB Gene

IDBG-146847 (Cd164)

Protein Structure

UniProt Annotation

Function

Sialomucin that may play a key role in hematopoiesis. May be involved in cell adhesion (By similarity). Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes. {ECO:0000250, ECO:0000269PubMed:18227060}.

Subcellular Localization

Lysosome membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Endosome membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed at high levels in the submaxillary gland and kidney, at moderate levels in the brain, heart, lung, liver, intestine, testis, muscle and bone marrow, and at low levels in the pancreas, spleen and thymus. {ECO:0000269PubMed:10491205, ECO:0000269PubMed:11027692}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007155	cell adhesion
GO:0007157	heterophilic cell-cell adhesion
GO:0007517	muscle organ development

Cellular Component

GO:0005764	lysosome
GO:0005765	lysosomal membrane
GO:0005768	endosome
GO:0005886	plasma membrane
GO:0010008	endosome membrane
GO:0016021	integral component of membrane