Version 5.4
Mus musculus Protein: Kcnt1
Summary
InnateDB Protein IDBP-147337.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcnt1
Protein Name potassium channel, subfamily T, member 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000039058
InnateDB Gene IDBG-147335 (Kcnt1)
Protein Structure
UniProt Annotation
Function Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro) (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005249 voltage-gated potassium channel activity
GO:0015269 calcium-activated potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:1924627
InterPro IPR003929 Potassium channel, calcium-activated, BK, alpha subunit
IPR013099 Two pore domain potassium channel domain
PFAM PF03493
PF07885
PRINTS PR01449
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZPR4
PhosphoSite PhosphoSite-Q6ZPR4
TrEMBL Q8C853
UniProt Splice Variant
Entrez Gene 227632
UniGene Mm.401525
RefSeq NP_780671
MGI ID
MGI Symbol Kcnt1
OMIM
CCDS CCDS15794
HPRD
IMGT
EMBL AK048406 AK086119 AK129355 AL731682 BC141190 BC171963
GenPept AAI41191 AAI71963 BAC33326 BAC39614 BAC98165

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca