Version 5.4
Homo sapiens Protein: ZC3H14
Summary
InnateDB Protein IDBP-15060.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZC3H14
Protein Name zinc finger CCCH-type containing 14
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000307025
InnateDB Gene IDBG-15058 (ZC3H14)
Protein Structure
UniProt Annotation
Function Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides. {ECO:0000269PubMed:17630287, ECO:0000269PubMed:24671764}.
Subcellular Localization Nucleus speckle {ECO:0000269PubMed:17630287, ECO:0000269PubMed:19303045, ECO:0000269PubMed:24671764}.Isoform 1: Nucleus speckle.Isoform 3: Nucleus speckle.Isoform 6: Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016607 nuclear speck
Protein Structure and Domains
PDB ID
InterPro IPR000571 Zinc finger, CCCH-type
PFAM PF00642
PRINTS
PIRSF
SMART SM00356
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PJT7
PhosphoSite PhosphoSite-Q6PJT7
TrEMBL G3V572
UniProt Splice Variant
Entrez Gene 79882
UniGene Hs.686171
RefSeq NP_997543
HUGO HGNC:20509
OMIM 613279
CCDS CCDS32134
HPRD 13348
IMGT
EMBL AF155107 AF474376 AK021868 AK302136 AK303123 AK304275 AL162171 AL834215 AY578060 AY578061 AY578062 AY578063 BC011793 BC023641 BC027607 BX248265 BX248281 BX248769 BX640716 BX640876 CH471061
GenPept AAD42873 AAH11793 AAH23641 AAH27607 AAL83289 AAS90299 AAS90300 AAS90301 AAS90302 BAG63510 BAG64229 BAG65136 CAD38897 CAD62593 CAD62609 CAD66576 CAE45835 CAE45933 EAW81384 EAW81385 EAW81387 EAW81388 EAW81389 EAW81390

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca