Version 5.4
Mus musculus Protein: Nmd3
Summary
InnateDB Protein IDBP-151610.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nmd3
Protein Name NMD3 homolog (S. cerevisiae)
Synonyms C87860;
Species Mus musculus
Ensembl Protein ENSMUSP00000029358
InnateDB Gene IDBG-151608 (Nmd3)
Protein Structure
UniProt Annotation
Function Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Nucleus, nucleoplasm {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Note=Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0030674 protein binding, bridging
GO:0043023 ribosomal large subunit binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000055 ribosomal large subunit export from nucleus
GO:0015031 protein transport
Cellular Component
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:2140103
InterPro IPR007064 NMD3
PFAM PF04981
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99L48
PhosphoSite PhosphoSite-Q99L48
TrEMBL D3YYX2
UniProt Splice Variant
Entrez Gene 97112
UniGene
RefSeq NP_598548
MGI ID
MGI Symbol Nmd3
OMIM
CCDS CCDS17407
HPRD
IMGT
EMBL AC115035 AC162790 AK034772 AK088667 AK143289 AK145248 AK166283 BC003842
GenPept AAH03842 BAC28829 BAC40491 BAE25334 BAE26326 BAE38680

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca