InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pycrl

Summary

InnateDB Protein

IDBP-151850.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pycrl

Protein Name

pyrroline-5-carboxylate reductase-like

Synonyms

1110058B13Rik; 2700073G24Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000049605

InnateDB Gene

IDBG-151848 (Pycrl)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	15 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004735	pyrroline-5-carboxylate reductase activity
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0006561	proline biosynthetic process
GO:0055114	oxidation-reduction process
GO:0055129	L-proline biosynthetic process

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:1913444

InterPro

IPR000304 Pyrroline-5-carboxylate reductase
IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal

PFAM

PF03807

PRINTS

PIRSF

PIRSF000193

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9DCC4