Version 5.4
Mus musculus Protein: Sh3rf1
Summary
InnateDB Protein IDBP-157101.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sh3rf1
Protein Name SH3 domain containing ring finger 1
Synonyms 2200003J05Rik; Posh; R75531; Sh3md2;
Species Mus musculus
Ensembl Protein ENSMUSP00000034060
InnateDB Gene IDBG-157099 (Sh3rf1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0046328 regulation of JNK cascade
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:1913066
InterPro IPR001452 SH3 domain
IPR001841 Zinc finger, RING-type
IPR011511 Variant SH3 domain
IPR018957 Zinc finger, C3HC4 RING-type
PFAM PF00018
PF14604
PF13639
PF14634
PF07653
PF00097
PRINTS PR00452
PIRSF
SMART SM00326
SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9QQ33
UniProt Splice Variant
Entrez Gene 59009
UniGene Mm.409109
RefSeq NP_067481
MGI ID
MGI Symbol Sh3rf1
OMIM
CCDS CCDS40348
HPRD
IMGT
EMBL AC117196 AC134339
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca