InnateDB Protein
|
IDBP-159894.5
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Last Modified
|
2012-02-14 [Report errors or provide feedback]
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Gene Symbol
|
Mef2d
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Protein Name
|
myocyte enhancer factor 2D
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Synonyms
|
C80750;
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Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000001455
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InnateDB Gene
|
IDBG-159892 (Mef2d)
|
Protein Structure
|
|
Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
|
This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Experimentally validated |
Total |
12
[view]
|
Protein-Protein |
7
[view]
|
Protein-DNA |
3
[view]
|
Protein-RNA |
2
[view]
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
31 [view]
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0000977
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RNA polymerase II regulatory region sequence-specific DNA binding
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GO:0000981
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sequence-specific DNA binding RNA polymerase II transcription factor activity
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GO:0003677
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DNA binding
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0005515
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protein binding
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GO:0033613
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activating transcription factor binding
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GO:0042826
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histone deacetylase binding
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GO:0046983
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protein dimerization activity
|
|
Biological Process |
GO:0001649
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osteoblast differentiation
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GO:0001958
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endochondral ossification
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GO:0002062
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chondrocyte differentiation
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GO:0006355
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regulation of transcription, DNA-templated
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GO:0006366
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transcription from RNA polymerase II promoter
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GO:0007512
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adult heart development
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GO:0035914
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skeletal muscle cell differentiation
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GO:0045893
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positive regulation of transcription, DNA-templated
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
|
|
Cellular Component |
|
PDB ID |
MGI:99533
|
InterPro |
IPR002100
Transcription factor, MADS-box
IPR022102
Holliday junction regulator protein family C-terminal
|
PFAM |
PF00319
PF12347
|
PRINTS |
PR00404
|
PIRSF |
|
SMART |
SM00432
|
TIGRFAMs |
|
Modification |
|
SwissProt |
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
Q921S6
|
UniProt Splice Variant |
|
Entrez Gene |
17261
|
UniGene |
Mm.485397
|
RefSeq |
NP_598426
|
MGI ID |
|
MGI Symbol |
Mef2d
|
OMIM |
|
CCDS |
CCDS38479
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HPRD |
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IMGT |
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EMBL |
AC137525
AK155778
BC011070
CH466547
|
GenPept |
AAH11070
BAE33434
EDL15313
|
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