InnateDB Protein
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IDBP-161261.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Hipk4
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Protein Name
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homeodomain interacting protein kinase 4
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000043175
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InnateDB Gene
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IDBG-161259 (Hipk4)
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Protein Structure
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Function |
Protein kinase that phosphorylates murine TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter. May act as a corepressor of transcription factors (Potential). {ECO:0000305}.
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:18022393}.
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Disease Associations |
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Tissue Specificity |
Expressed at moderate levels in lung and white adipose tissues and weakly in brain and liver. {ECO:0000269PubMed:18022393}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
Accession |
GO Term |
GO:0004672
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protein kinase activity
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GO:0004674
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protein serine/threonine kinase activity
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GO:0005524
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ATP binding
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GO:0016772
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transferase activity, transferring phosphorus-containing groups
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2685008
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InterPro |
IPR011009
Protein kinase-like domain
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q3V016
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PhosphoSite |
PhosphoSite-Q3V016
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
233020
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UniGene |
Mm.429716
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RefSeq |
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MGI ID |
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MGI Symbol |
Hipk4
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AB354583
AC158304
AK133498
BC147572
BC147577
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GenPept |
AAI47573
AAI47578
BAE21689
BAF93448
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