Version 5.4
Mus musculus Protein: Dppa4
Summary
InnateDB Protein IDBP-164250.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dppa4
Protein Name developmental pluripotency associated 4
Synonyms 2410091M23Rik; C76608; ECAT15-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000093749
InnateDB Gene IDBG-164248 (Dppa4)
Protein Structure
UniProt Annotation
Function May be involved in the maintenance of active epigenetic status of target genes. May inhibit differentiation of embryonic stem (ES) cells into a primitive ectoderm lineage. {ECO:0000269PubMed:17855347, ECO:0000269PubMed:21896782}.
Subcellular Localization Nucleus {ECO:0000269PubMed:17855347, ECO:0000269PubMed:21896782}. Note=Associated with transcriptionally active chromatin.
Disease Associations
Tissue Specificity Expressed in pluripotent embryonic cells, but not in differentiated somatic tissues. {ECO:0000269PubMed:12620990, ECO:0000269PubMed:17855347, ECO:0000269PubMed:21896782}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0060484 lung-associated mesenchyme development
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2157525
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CCG4
PhosphoSite PhosphoSite-Q8CCG4
TrEMBL
UniProt Splice Variant
Entrez Gene 73693
UniGene Mm.35597
RefSeq NP_082886
MGI ID
MGI Symbol Dppa4
OMIM
CCDS CCDS28209
HPRD
IMGT
EMBL AF490348 AK033197 BC064754
GenPept AAH64754 AAO84506 BAC28194

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca