InnateDB Protein
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IDBP-164561.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Snrpg
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Protein Name
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small nuclear ribonucleoprotein polypeptide G
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Synonyms
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2810024K17Rik; AL022803; sm-G; SMG; snRNP-G;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000086987
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InnateDB Gene
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IDBG-164559 (Snrpg)
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Protein Structure
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Function |
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. Appears to function in the U7 snRNP complex that is involved in histone 3'- end processing (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1915261
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InterPro |
IPR001163
Ribonucleoprotein LSM domain
IPR006649
Ribonucleoprotein LSM domain, eukaryotic/archaea-type
IPR010920
Like-Sm (LSM) domain
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PFAM |
PF01423
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PRINTS |
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PIRSF |
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SMART |
SM00651
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TIGRFAMs |
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Modification |
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SwissProt |
P62309
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PhosphoSite |
PhosphoSite-P62309
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TrEMBL |
Q3V424
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UniProt Splice Variant |
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Entrez Gene |
68011
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UniGene |
Mm.473188
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RefSeq |
NP_080782
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MGI ID |
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MGI Symbol |
Snrpg
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OMIM |
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CCDS |
CCDS39541
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HPRD |
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IMGT |
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EMBL |
AK012802
AK013235
AK017852
BC027499
BC051470
BC094411
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GenPept |
AAH27499
AAH51470
AAH94411
BAB28480
BAB28732
BAE43250
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