InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Arap2

Summary

InnateDB Protein

IDBP-165167.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Arap2

Protein Name

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000075924

InnateDB Gene

IDBG-165165 (Arap2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
GO:0008060	ARF GTPase activator activity
GO:0008270	zinc ion binding

Biological Process

GO:0007165	signal transduction
GO:0032312	regulation of ARF GTPase activity
GO:0043547	positive regulation of GTPase activity

Cellular Component

GO:0005622

intracellular

Protein Structure and Domains

PDB ID

MGI:2684416

InterPro

IPR000159 Ras-association
IPR000198 Rho GTPase-activating protein domain
IPR001164 Arf GTPase activating protein
IPR001660 Sterile alpha motif domain
IPR001849 Pleckstrin homology domain
IPR008936 Rho GTPase activation protein
IPR011510 Sterile alpha motif, type 2
IPR013761 Sterile alpha motif/pointed domain
IPR021129 Sterile alpha motif, type 1
IPR029071 Ubiquitin-related domain

PFAM

PF00788
PF00620
PF01412
PF00169
PF07647
PF00536

PRINTS

PR00405

PIRSF

SMART

SM00314
SM00324
SM00105
SM00454
SM00233

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt