InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cdx4

Summary

InnateDB Protein

IDBP-165734.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cdx4

Protein Name

caudal type homeobox 4

Synonyms

Cdx-3; Cdx-4; Cdx3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000033689

InnateDB Gene

IDBG-165732 (Cdx4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000976	transcription regulatory region sequence-specific DNA binding
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001568	blood vessel development
GO:0001890	placenta development
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007275	multicellular organismal development
GO:0009952	anterior/posterior pattern specification
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0060711	labyrinthine layer development

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:88362

InterPro

IPR000047 Helix-turn-helix motif
IPR001356 Homeobox domain
IPR006820 Caudal-like activation domain
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa

PFAM

PF00046
PF04731

PRINTS

PR00031
PR00024

PIRSF

SMART

SM00389

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt