InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cherp

Summary

InnateDB Protein

IDBP-168124.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cherp

Protein Name

calcium homeostasis endoplasmic reticulum protein

Synonyms

5730408I11Rik; D8Wsu96e; DAN16; Scaf6;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000078469

InnateDB Gene

IDBG-168122 (Cherp)

Protein Structure

UniProt Annotation

Function

Involved in calcium homeostasis, growth and proliferation. {ECO:0000250UniProtKB:Q8IWX8}.

Subcellular Localization

Cytoplasm {ECO:0000250UniProtKB:Q8IWX8}. Cytoplasm, perinuclear region {ECO:0000250UniProtKB:Q8IWX8}. Endoplasmic reticulum {ECO:0000250UniProtKB:Q8IWX8}. Note=Distributed throughout the cytoplasm and also localizes to the perinuclear region. Colocalizes with ITPR1 (By similarity). {ECO:0000250UniProtKB:Q8IWX8}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	33 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0044325	ion channel binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006396	RNA processing
GO:0006874	cellular calcium ion homeostasis
GO:0008285	negative regulation of cell proliferation
GO:0051209	release of sequestered calcium ion into cytosol
GO:0051533	positive regulation of NFAT protein import into nucleus