Version 5.4
| Mus musculus Protein: Zfp354c | |||||||||||
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| Summary | |||||||||||
| InnateDB Protein | IDBP-169041.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Zfp354c | ||||||||||
| Protein Name | zinc finger protein 354C | ||||||||||
| Synonyms | 5330421P20Rik; AJ18; AW743325; Kid3; mKIAA4218; Tcf17l2; Znf354c; | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Protein | ENSMUSP00000000632 | ||||||||||
| InnateDB Gene | IDBG-169039 (Zfp354c) | ||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||
| Function | May function as a transcription repressor. Suppresses osteogenic effects of RUNX2. Binds to 5'-CCACA-3' core sequence. May be involved in osteoblastic differentiation (By similarity). {ECO:0000250}. | ||||||||||
| Subcellular Localization | Nucleus {ECO:0000250}. | ||||||||||
| Disease Associations | |||||||||||
| Tissue Specificity | Expressed in brain. Lower levels in kidney, heart, lung, spleen and eye. Down-regulated during kidney maturation. {ECO:0000269PubMed:10786630}. | ||||||||||
| Comments | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||
| PDB ID | MGI:1353621 | ||||||||||
| InterPro |
IPR001909
Krueppel-associated box IPR007087 Zinc finger, C2H2 IPR015880 Zinc finger, C2H2-like |
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| PFAM |
PF01352
PF00096 |
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| PRINTS | |||||||||||
| PIRSF | |||||||||||
| SMART |
SM00349
SM00355 |
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| TIGRFAMs | |||||||||||
| Post-translational Modifications | |||||||||||
| Modification | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q571J5 | ||||||||||
| PhosphoSite | PhosphoSite-Q571J5 | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 30944 | ||||||||||
| UniGene | Mm.471339 | ||||||||||
| RefSeq | |||||||||||
| MGI ID | |||||||||||
| MGI Symbol | Zfp354c | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS24637 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | AF192804 AK086760 AK145882 AK220194 AL627215 BC079908 | ||||||||||
| GenPept | AAF35173 AAH79908 BAC39738 BAD90379 BAE26722 CAI35293 | ||||||||||