InnateDB Protein
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IDBP-170421.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Tpgs1
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Protein Name
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predicted gene, Gm16517
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Synonyms
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AV005629; Gm16517; Gtrgeo22; PGs1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000020552
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InnateDB Gene
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IDBG-170419 (Tpgs1)
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Protein Structure
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Function |
May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum. {ECO:0000269PubMed:12242242, ECO:0000269PubMed:12972506, ECO:0000269PubMed:15890843}.
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Subcellular Localization |
Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269PubMed:12972506}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269PubMed:12972506}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269PubMed:12972506}. Cytoplasm, cytoskeleton, flagellum basal body {ECO:0000269PubMed:12972506}. Cell projection, axon {ECO:0000269PubMed:12972506}. Cell projection, dendrite {ECO:0000269PubMed:12972506}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269PubMed:12972506}. Note=Associated with microtubules from neurites, centrosomes, basal bodies and axonemes.
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Disease Associations |
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Tissue Specificity |
Broadly expressed at low levels. Highly expressed in brain. Present in brain neurons (at protein level). {ECO:0000269PubMed:12242242, ECO:0000269PubMed:12972506}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:106618
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InterPro |
IPR003117
Dimerization-anchoring domain of cAMP-dependent protein kinase, regulatory subunit
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PFAM |
PF02197
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PRINTS |
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PIRSF |
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SMART |
SM00394
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TIGRFAMs |
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Modification |
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SwissProt |
Q99MS8
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PhosphoSite |
PhosphoSite-Q99MS8
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TrEMBL |
B2RRP1
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UniProt Splice Variant |
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Entrez Gene |
110012
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UniGene |
Mm.22623
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RefSeq |
NP_683736
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MGI ID |
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MGI Symbol |
Tpgs1
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OMIM |
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CCDS |
CCDS23982
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HPRD |
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IMGT |
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EMBL |
AF084937
AF303106
AK153467
BC138515
BC138516
CH466553
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GenPept |
AAD54650
AAI38516
AAI38517
AAK15262
BAE32018
EDL31681
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