InnateDB Protein
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IDBP-17185.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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VOPP1
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Protein Name
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vesicular, overexpressed in cancer, prosurvival protein 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000285279
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InnateDB Gene
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IDBG-17183 (VOPP1)
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Protein Structure
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Function |
Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. {ECO:0000269PubMed:15735698}.
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Subcellular Localization |
Cytoplasmic vesicle membrane {ECO:0000269PubMed:20571887}; Single-pass type I membrane protein {ECO:0000269PubMed:20571887}. Note=When overexpressed, localizes in the nucleus and perinuclear regions.
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Disease Associations |
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Tissue Specificity |
Widely expressed with highest levels in thymus and ovary. {ECO:0000269PubMed:11916499}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0004871
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signal transducer activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q96AW1
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PhosphoSite |
PhosphoSite-Q96AW1
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TrEMBL |
C9JTY8
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UniProt Splice Variant |
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Entrez Gene |
81552
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UniGene |
Hs.738657
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RefSeq |
NP_110423
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HUGO |
HGNC:34518
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OMIM |
611915
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CCDS |
CCDS47588
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HPRD |
08526
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IMGT |
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EMBL |
AB097004
AC073237
AC073347
AC099681
AF395824
AK075391
AK092992
AK314338
AK315882
AL136610
BC016650
CH236957
CH471201
CR533483
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GenPept |
AAH16650
AAK82888
BAC11590
BAC77357
BAF98773
BAG36981
BAG52634
CAB66545
CAG38514
EAL23811
EAW50969
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