InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rexo1

Summary

InnateDB Protein

IDBP-174536.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rexo1

Protein Name

REX1, RNA exonuclease 1 homolog (S. cerevisiae)

Synonyms

1700021P10Rik; 2610511M11Rik; AW050347; EloA-BP1; Tceb3bp1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000049705

InnateDB Gene

IDBG-174534 (Rexo1)

Protein Structure

UniProt Annotation

Function

Seems to have no detectable effect on transcription elongation in vitro. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003676	nucleic acid binding
GO:0004527	exonuclease activity

Biological Process

GO:0008150	biological_process
GO:0090305	nucleic acid phosphodiester bond hydrolysis

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:1914182

InterPro

IPR006055 Exonuclease
IPR012337 Ribonuclease H-like domain
IPR013520 Exonuclease, RNase T/DNA polymerase III

PFAM

PF00929

PRINTS

PIRSF

SMART

SM00479

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q7TT28

PhosphoSite

PhosphoSite-Q7TT28

TrEMBL

UniProt Splice Variant

Entrez Gene

66932

UniGene

Mm.1116

RefSeq

NP_080128

MGI ID

MGI Symbol

Rexo1

OMIM

CCDS

CCDS24025

HPRD

IMGT

EMBL

AK006228 AK144769 AK173108 BC039623 BC052424 BC069964

GenPept

AAH39623 AAH52424 AAH69964 BAB24471 BAD32386 BAE26057