Version 5.4
Mus musculus Protein: Car12
Summary
InnateDB Protein IDBP-179859.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Car12
Protein Name carbonic anyhydrase 12
Synonyms 2310047E01Rik; AI314958; Ca12;
Species Mus musculus
Ensembl Protein ENSMUSP00000071786
InnateDB Gene IDBG-179857 (Car12)
Protein Structure
UniProt Annotation
Function Reversible hydration of carbon dioxide.
Subcellular Localization Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 1 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006730 one-carbon metabolic process
GO:0006885 regulation of pH
GO:0015670 carbon dioxide transport
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1923709
InterPro IPR001148 Alpha carbonic anhydrase
PFAM PF00194
PRINTS
PIRSF
SMART SM01057
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CI85
PhosphoSite PhosphoSite-Q8CI85
TrEMBL
UniProt Splice Variant
Entrez Gene 76459
UniGene Mm.277921
RefSeq NP_848483
MGI ID
MGI Symbol Car12
OMIM
CCDS CCDS23306
HPRD
IMGT
EMBL AK052639 BC035941
GenPept AAH35941 BAC35074

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca