InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Agps

Summary

InnateDB Protein

IDBP-181525.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Agps

Protein Name

alkylglycerone phosphate synthase

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000041967

InnateDB Gene

IDBG-181523 (Agps)

Protein Structure

UniProt Annotation

Function

Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. {ECO:0000250}.

Subcellular Localization

Peroxisome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0008609	alkylglycerone-phosphate synthase activity
GO:0008762	UDP-N-acetylmuramate dehydrogenase activity
GO:0016491	oxidoreductase activity
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
GO:0050660	flavin adenine dinucleotide binding
GO:0071949	FAD binding

Biological Process

GO:0008610	lipid biosynthetic process
GO:0008611	ether lipid biosynthetic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005730	nucleolus
GO:0005739	mitochondrion
GO:0005777	peroxisome
GO:0005778	peroxisomal membrane
GO:0016020	membrane
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

MGI:2443065

InterPro

IPR004113 FAD-linked oxidase, C-terminal
IPR006094 FAD linked oxidase, N-terminal
IPR016164 FAD-linked oxidase-like, C-terminal
IPR016166 FAD-binding, type 2

PFAM

PF02913
PF01565

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8C0I1

PhosphoSite