InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pllp

Summary

InnateDB Protein

IDBP-182561.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pllp

Protein Name

plasma membrane proteolipid

Synonyms

0610010I06Rik; AV001002; Plapi; Tm4sf11;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034227

InnateDB Gene

IDBG-182559 (Pllp)

Protein Structure

UniProt Annotation

Function

Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective (By similarity). {ECO:0000250}.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0006811	ion transport
GO:0009611	response to wounding
GO:0042552	myelination

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043218	compact myelin
GO:0045121	membrane raft
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1915051

InterPro

IPR008253 Marvel domain
IPR013295 Myelin and lymphocyte (MAL) protein

PFAM

PF01284

PRINTS

PR01884

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9DCU2

PhosphoSite

PhosphoSite-Q9DCU2

TrEMBL

UniProt Splice Variant

Entrez Gene

67801

UniGene

Mm.396674

RefSeq

NP_080661

MGI ID

MGI Symbol

Pllp

OMIM

CCDS

CCDS22546

HPRD

IMGT

EMBL

AJ298129 AJ298130 AK002477 AK032540 BC024534

GenPept

AAH24534 BAB22130 BAC27916 CAC88126