InnateDB Protein
|
IDBP-18391.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
RPL21
|
Protein Name
|
ribosomal protein L21
|
Synonyms
|
HYPT12; L21;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000346027
|
InnateDB Gene
|
IDBG-18389 (RPL21)
|
Protein Structure
|
|
Function |
|
Subcellular Localization |
|
Disease Associations |
Note=Defects in RPL21 are a cause of generalized hypotrichosis simplex (HTS). A rare form of non-syndromic hereditary hypotrichosis without characteristic hair shaft anomalies. Affected individuals typically show normal hair at birth, but hair loss and thinning of the hair shaft start during early childhood and progress with age.
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 121 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
121
[view]
|
Protein-Protein |
121
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR001147
Ribosomal protein L21e
IPR008991
Translation protein SH3-like domain
|
PFAM |
PF01157
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
P46778
|
PhosphoSite |
PhosphoSite-P46778
|
TrEMBL |
Q6IAX2
|
UniProt Splice Variant |
|
Entrez Gene |
619499
|
UniGene |
Hs.720640
|
RefSeq |
NP_000973
|
HUGO |
HGNC:10313
|
OMIM |
603636
|
CCDS |
CCDS9320
|
HPRD |
04700
|
IMGT |
|
EMBL |
AB007176
AB061826
AK311795
AL159977
BC001603
BC007505
BC062981
BC070184
BC070323
BC070330
BC071902
BC104667
CH471075
CR457032
L38826
U14967
U25789
X89401
|
GenPept |
AAA80462
AAA85655
AAA93231
AAH01603
AAH07505
AAH62981
AAH70184
AAH70323
AAH70330
AAH71902
AAI04668
BAA25835
BAB79464
BAG34738
CAA61582
CAG33313
EAX08395
EAX08398
|
|
|