Mus musculus Protein: Cnot1
Summary
InnateDB Protein IDBP-184244.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cnot1
Protein Name CCR4-NOT transcription complex, subunit 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000063565
InnateDB Gene IDBG-184242 (Cnot1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 40 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004535 poly(A)-specific ribonuclease activity
GO:0005488 binding
GO:0005515 protein binding
GO:0030331 estrogen receptor binding
GO:0042974 retinoic acid receptor binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly
GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway
GO:0048387 negative regulation of retinoic acid receptor signaling pathway
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic
GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:2000036 regulation of stem cell maintenance
Cellular Component
GO:0005778 peroxisomal membrane
GO:0030014 CCR4-NOT complex
Protein Structure and Domains
PDB ID MGI:2442402
InterPro IPR007196 CCR4-Not complex component, Not1, C-terminal
IPR016024 Armadillo-type fold
PFAM PF04054
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B7ZWL1
UniProt Splice Variant
Entrez Gene 620499
UniGene Mm.415682
RefSeq NP_694804
MGI ID
MGI Symbol Cnot1
OMIM
CCDS CCDS57635
HPRD
IMGT
EMBL AC113951 AC127300 BC172105
GenPept AAI72105