Homo sapiens Protein: ADAM32
Summary
InnateDB Protein IDBP-18459.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAM32
Protein Name ADAM metallopeptidase domain 32
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000369238
InnateDB Gene IDBG-18455 (ADAM32)
Protein Structure
UniProt Annotation
Function May play a role in sperm development and fertilization This is a non-catalytic metalloprotease-like protein. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Testis specific. {ECO:0000269PubMed:12568724}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000742 Epidermal growth factor-like domain
IPR001590 Peptidase M12B, ADAM/reprolysin
IPR001762 Blood coagulation inhibitor, Disintegrin
IPR002870 Peptidase M12B, propeptide
IPR006586 ADAM, cysteine-rich
PFAM PF00008
PF01421
PF00200
PF01562
PF08516
PRINTS PR00289
PIRSF
SMART SM00181
SM00050
SM00608
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TC27
PhosphoSite PhosphoSite-Q8TC27
TrEMBL E5RJY7
UniProt Splice Variant
Entrez Gene 203102
UniGene Hs.679710
RefSeq NP_659441
HUGO HGNC:15479
OMIM
CCDS CCDS47846
HPRD 16475
IMGT
EMBL AC105091 AC105185 AY358739 BC026085 BC026169 BC028702 BC030014 BC030698 BC034975
GenPept AAH26085 AAH26169 AAH28702 AAH30014 AAH30698 AAH34975 AAQ89099