InnateDB Protein
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IDBP-18515.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ACSM1
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Protein Name
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acyl-CoA synthetase medium-chain family member 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000301956
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InnateDB Gene
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IDBG-18511 (ACSM1)
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Protein Structure
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Function |
Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro). Functions as GTP-dependent lipoate- activating enzyme that generates the substrate for lipoyltransferase (By similarity). {ECO:0000250}.
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Subcellular Localization |
Mitochondrion matrix {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000873
AMP-dependent synthetase/ligase
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PFAM |
PF00501
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q08AH1
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PhosphoSite |
PhosphoSite-Q08AH1
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TrEMBL |
E5RFK0
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UniProt Splice Variant |
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Entrez Gene |
116285
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UniGene |
Hs.306812
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RefSeq |
NP_443188
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HUGO |
HGNC:18049
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OMIM |
614357
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CCDS |
CCDS10587
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HPRD |
12551
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IMGT |
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EMBL |
AB059429
AB062503
AC020926
AC141273
BC125177
BC125178
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GenPept |
AAI25178
AAI25179
BAB64535
BAB68363
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