Version 5.4
Mus musculus Protein: Sypl2
Summary
InnateDB Protein IDBP-186633.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sypl2
Protein Name synaptophysin-like 2
Synonyms AI552439; Mg29;
Species Mus musculus
Ensembl Protein ENSMUSP00000029486
InnateDB Gene IDBG-186631 (Sypl2)
Protein Structure
UniProt Annotation
Function Involved in communication between the T-tubular and junctional sarcoplasmic reticulum (SR) membranes. {ECO:0000250}.
Subcellular Localization Membrane; Multi-pass membrane protein. Note=Triad junction, the junctional complex between the transverse tubule and the sarcoplasmic reticulum.
Disease Associations
Tissue Specificity Expressed abundantly in skeletal muscle and at lower levels in the kidney. {ECO:0000269PubMed:9708916}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
Biological Process
GO:0006810 transport
GO:0006874 cellular calcium ion homeostasis
Cellular Component
GO:0016020 membrane
GO:0030285 integral component of synaptic vesicle membrane
Protein Structure and Domains
PDB ID MGI:1328311
InterPro IPR001285 Synaptophysin/synaptoporin
IPR008253 Marvel domain
PFAM PF01284
PRINTS PR00220
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O89104
PhosphoSite PhosphoSite-O89104
TrEMBL Q8BNK8
UniProt Splice Variant
Entrez Gene 17306
UniGene Mm.316885
RefSeq NP_032622
MGI ID
MGI Symbol Sypl2
OMIM
CCDS CCDS57253
HPRD
IMGT
EMBL AB010140 AB010144 AK083422 BC030038
GenPept AAH30038 BAA32530 BAA32531 BAC38909

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca