InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tppp3

Summary

InnateDB Protein

IDBP-187807.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tppp3

Protein Name

tubulin polymerization-promoting protein family member 3

Synonyms

2700055K07Rik; Ceacam9; CGI-38; mmCGM8;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000014990

InnateDB Gene

IDBG-187805 (Tppp3)

Protein Structure

UniProt Annotation

Function

Binds tubulin and has microtubule bundling activity. May play a role in cell proliferation and mitosis (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015631	tubulin binding

Biological Process

GO:0001578

microtubule bundle formation

Cellular Component

GO:0005575	cellular_component
GO:0005737	cytoplasm
GO:0005874	microtubule
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1915221

InterPro

IPR008907 P25-alpha

PFAM

PF05517

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9CRB6

PhosphoSite

PhosphoSite-Q9CRB6

TrEMBL

UniProt Splice Variant

Entrez Gene

67971

UniGene

Mm.29358

RefSeq

NP_080757

MGI ID

1WLM

MGI Symbol

Tppp3

OMIM

CCDS

CCDS22602

HPRD

IMGT

EMBL

AK009771 AK012437 AK155018 AK160507 BC010788

GenPept

AAH10788 BAB26493 BAB28237 BAE32991 BAE35831