InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ccdc59

Summary

InnateDB Protein

IDBP-188698.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ccdc59

Protein Name

coiled-coil domain containing 59

Synonyms

2300004H16Rik; D10Ertd718e;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000020049

InnateDB Gene

IDBG-188696 (Ccdc59)

Protein Structure

UniProt Annotation

Function

Component of the transcription complexes of the pulmonary surfactant-associated protein-B (SFTPB) and -C (SFTPC). Enhances homeobox protein Nkx-2.1-activated SFTPB and SFTPC promoter activities (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0008150	biological_process

Cellular Component

GO:0005575	cellular_component
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

MGI:1289302

InterPro

IPR013730 rRNA processing

PFAM

PF08524

PRINTS

PR01854

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8R2N0

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

52713

UniGene

Mm.339224

RefSeq

NP_079878

MGI ID

MGI Symbol

Ccdc59

OMIM

CCDS

CCDS24158

HPRD

IMGT

EMBL

AK009028 AK012917 AK019970 AK036330 AK135550 BC027401

GenPept

AAH27401 BAB26036 BAB28548 BAB31941 BAC29386 BAE22578