Version 5.4
Homo sapiens Protein: LYRM1
Summary
InnateDB Protein IDBP-18885.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LYRM1
Protein Name LYR motif containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000219168
InnateDB Gene IDBG-18883 (LYRM1)
Protein Structure
UniProt Annotation
Function May promote cell proliferation and inhibition of apoptosis of preadipocytes. {ECO:0000269PubMed:19022914}.
Subcellular Localization Nucleus {ECO:0000269PubMed:19022914}.
Disease Associations Note=When overexpressed, may be involved in obesity- associated insulin resistance, possibly by causing mitochondrial dysfunction in adipocytes.
Tissue Specificity High levels in adipose tissue. {ECO:0000269PubMed:19022914}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR008011 Complex 1 LYR protein
PFAM PF05347
PF13232
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O43325
PhosphoSite PhosphoSite-
TrEMBL H3BNA8
UniProt Splice Variant
Entrez Gene 57149
UniGene Hs.743408
RefSeq NP_001121774
HUGO HGNC:25074
OMIM 614709
CCDS CCDS10593
HPRD 14254
IMGT
EMBL AC002394 AK311881 BC017039 CH471228
GenPept AAC05810 AAH17039 BAG34822 EAW66847 EAW66849

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca