InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gtf2f1

Summary

InnateDB Protein

IDBP-193307.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gtf2f1

Protein Name

general transcription factor IIF, polypeptide 1

Synonyms

2810405L04Rik; C76800; RAP74;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000002733

InnateDB Gene

IDBG-193303 (Gtf2f1)

Protein Structure

UniProt Annotation

Function

TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 57 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	57 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003824	catalytic activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0019211	phosphatase activator activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0009615	response to virus
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
GO:0043085	positive regulation of catalytic activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter