InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Trnau1ap

Summary

InnateDB Protein

IDBP-193820.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Trnau1ap

Protein Name

tRNA selenocysteine 1 associated protein 1

Synonyms

1110007F05Rik; AA387999; Secp43; Trspap1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000030730

InnateDB Gene

IDBG-193818 (Trnau1ap)

Protein Structure

UniProt Annotation

Function

Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis. {ECO:0000269PubMed:16230358, ECO:0000269PubMed:16508009}.

Subcellular Localization

Nucleus. Cytoplasm. Note=Abundant in the nucleus. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding