Version 5.4
Mus musculus Protein: Zmynd15
Summary
InnateDB Protein IDBP-194431.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zmynd15
Protein Name zinc finger, MYND-type containing 15
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000048816
InnateDB Gene IDBG-194429 (Zmynd15)
Protein Structure
UniProt Annotation
Function Acts as a transcriptional repressor through interaction with histone deacetylases (HDACs). May regulate haploid genes important for spermiogenesis. {ECO:0000269PubMed:20675388}.
Subcellular Localization Nucleus {ECO:0000269PubMed:20675388}. Cytoplasm {ECO:0000269PubMed:20675388}. Note=In step 9-11 spermatids, shifts from nucleus to cytoplasm.
Disease Associations
Tissue Specificity Testis-specific. Expressed in pachytene spermatocytes and all developing spermatids, but not in Sertoli, nor Leydig cells (at protein level). {ECO:0000269PubMed:20675388}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0042826 histone deacetylase binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0007286 spermatid development
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:3603821
InterPro IPR002893 Zinc finger, MYND-type
PFAM PF01753
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C0R7
PhosphoSite PhosphoSite-
TrEMBL J3QK22
UniProt Splice Variant
Entrez Gene 574428
UniGene Mm.472771
RefSeq NP_001025100
MGI ID
MGI Symbol Zmynd15
OMIM
CCDS CCDS24949
HPRD
IMGT
EMBL AK029988 AK171931 AL596096 BC151086 CR936841
GenPept AAI51087 BAC26719 BAE42737 CAI51992 CAM28192

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca