Version 5.4
Mus musculus Protein: Mphosph6
Summary
InnateDB Protein IDBP-195233.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mphosph6
Protein Name M phase phosphoprotein 6
Synonyms 1110001M01Rik; AA536809; C86426;
Species Mus musculus
Ensembl Protein ENSMUSP00000034303
InnateDB Gene IDBG-195231 (Mphosph6)
Protein Structure
UniProt Annotation
Function RNA-binding protein that associates with the RNA exosome complex. Involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and may play a role in recruiting the RNA exosome complex to pre-rRNA; this function may include C1D (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nucleolus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Cytoplasmic in M phase. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
Predicted by orthology
Total 32 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000460 maturation of 5.8S rRNA
Cellular Component
GO:0000178 exosome (RNase complex)
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1915783
InterPro IPR019324 M-phase phosphoprotein 6
PFAM PF10175
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D1Q1
PhosphoSite PhosphoSite-Q9D1Q1
TrEMBL
UniProt Splice Variant
Entrez Gene 68533
UniGene Mm.397907
RefSeq NP_081034
MGI ID
MGI Symbol Mphosph6
OMIM
CCDS CCDS22702
HPRD
IMGT
EMBL AK003245 BC008161
GenPept AAH08161 BAB22664

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca