InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PLIN3

Summary

InnateDB Protein

IDBP-19540.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PLIN3

Protein Name

perilipin 3

Synonyms

M6PRBP1; PP17; TIP47;

Species

Homo sapiens

Ensembl Protein

ENSP00000221957

InnateDB Gene

IDBG-19538 (PLIN3)

Protein Structure

UniProt Annotation

Function

Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network. {ECO:0000269PubMed:9590177}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:15545278, ECO:0000269PubMed:9590177}. Endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Lipid droplet {ECO:0000305}. Note=Membrane associated on endosomes. Detected in the envelope and the core of lipid bodies and in lipid sails.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 52 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	52 [view]
Protein-Protein	50 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0016192

vesicle-mediated transport

Cellular Component

GO:0005737	cytoplasm
GO:0005768	endosome
GO:0005794	Golgi apparatus
GO:0005811	lipid particle
GO:0010008	endosome membrane
GO:0016020	membrane
GO:0043231	intracellular membrane-bounded organelle