Version 5.4
Mus musculus Protein: Prim1
Summary
InnateDB Protein IDBP-196332.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prim1
Protein Name DNA primase, p49 subunit
Synonyms AI324982;
Species Mus musculus
Ensembl Protein ENSMUSP00000026461
InnateDB Gene IDBG-196330 (Prim1)
Protein Structure
UniProt Annotation
Function DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003896 DNA primase activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006269 DNA replication, synthesis of RNA primer
Cellular Component
GO:0016020 membrane
GO:1990077 primosome complex
Protein Structure and Domains
PDB ID MGI:97757
InterPro IPR002755 DNA primase, small subunit
IPR014052 DNA primase, small subunit, eukaryotic/archaeal
PFAM PF01896
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P20664
PhosphoSite PhosphoSite-P20664
TrEMBL Q5FW94
UniProt Splice Variant
Entrez Gene 19075
UniGene Mm.2903
RefSeq NP_032947
MGI ID
MGI Symbol Prim1
OMIM
CCDS CCDS36086
HPRD
IMGT
EMBL AK088557 AK089063 BC089544 D13544 J04620
GenPept AAA39880 AAH89544 BAA02744 BAC40422 BAC40729

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca