Version 5.4
Mus musculus Protein: Casc5
Summary
InnateDB Protein IDBP-198803.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Casc5
Protein Name cancer susceptibility candidate 5
Synonyms 2310043D08Rik; 5730505K17Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000028802
InnateDB Gene IDBG-198797 (Casc5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008608 attachment of spindle microtubules to kinetochore
GO:0010923 negative regulation of phosphatase activity
GO:0034501 protein localization to kinetochore
GO:0071173 spindle assembly checkpoint
Cellular Component
GO:0001669 acrosomal vesicle
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1923714
InterPro IPR010310 Type VII secretion system ESAT-6-like
PFAM PF06013
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9CYF0
UniProt Splice Variant
Entrez Gene 76464
UniGene Mm.481433
RefSeq XP_006500439
MGI ID
MGI Symbol Casc5
OMIM
CCDS CCDS38203
HPRD
IMGT
EMBL AK017750 AL772264
GenPept BAB30909

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca