InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Eif4g3

Summary

InnateDB Protein

IDBP-199273.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Eif4g3

Protein Name

eukaryotic translation initiation factor 4 gamma, 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000081232

InnateDB Gene

IDBG-199269 (Eif4g3)

Protein Structure

UniProt Annotation

Function

Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be a functional homolog of EIF4G1 (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003743	translation initiation factor activity
GO:0005488	binding
GO:0005515	protein binding

Biological Process

GO:0001934	positive regulation of protein phosphorylation
GO:0006413	translational initiation
GO:0007283	spermatogenesis
GO:0045727	positive regulation of translation
GO:0060903	positive regulation of meiosis I