InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dhx57

Summary

InnateDB Protein

IDBP-199814.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dhx57

Protein Name

DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57

Synonyms

AW494914;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000083742

InnateDB Gene

IDBG-199810 (Dhx57)

Protein Structure

UniProt Annotation

Function

Probable ATP-binding RNA helicase.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0044822	poly(A) RNA binding
GO:0046872	metal ion binding

Biological Process

GO:0008150	biological_process
GO:0008152	metabolic process

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:2147067

InterPro

IPR000571 Zinc finger, CCCH-type
IPR001650 Helicase, C-terminal
IPR006575 RWD domain
IPR007502 Helicase-associated domain
IPR009060 UBA-like
IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR011709 Domain of unknown function DUF1605
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR015940 Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote
IPR016135 Ubiquitin-conjugating enzyme/RWD-like
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00642
PF00271
PF05773
PF04408
PF00270
PF07717

PRINTS

PIRSF

SMART

SM00356
SM00490
SM00591
SM00847
SM00487
SM00165

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q6P5D3