InnateDB Protein
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IDBP-200548.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Tsnax
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Protein Name
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translin-associated factor X
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Synonyms
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R74833; Trax;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000075290
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InnateDB Gene
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IDBG-200546 (Tsnax)
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Protein Structure
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Function |
Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, perinuclear region {ECO:0000250}. Golgi apparatus {ECO:0000269PubMed:15314092}. Nucleus {ECO:0000250}. Note=Expressed in the cytoplasm in the presence of TSN (By similarity). Accumulate in the Golgi complex of mid-late pachytene spermatocytes. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Detected in heart, brain, lung, liver, kidney and testis. {ECO:0000269PubMed:10790540}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated |
Total |
7
[view]
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Protein-Protein |
7
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
19 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1855672
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InterPro |
IPR002848
Translin
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PFAM |
PF01997
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9QZE7
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PhosphoSite |
PhosphoSite-Q9QZE7
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
53424
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UniGene |
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RefSeq |
NP_058605
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MGI ID |
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MGI Symbol |
Tsnax
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OMIM |
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CCDS |
CCDS22778
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HPRD |
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IMGT |
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EMBL |
AF187040
AK030407
AK146339
BC004611
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GenPept |
AAF05529
AAH04611
BAC26948
BAE27093
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