InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Snap23

Summary

InnateDB Protein

IDBP-201122.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Snap23

Protein Name

synaptosomal-associated protein 23

Synonyms

23kDa; AA408749; SNAP-23; Sndt; Syndet;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000028743

InnateDB Gene

IDBG-201120 (Snap23)

Protein Structure

UniProt Annotation

Function

Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. {ECO:0000250}.

Subcellular Localization

Cell membrane; Peripheral membrane protein. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Cell junction, synapse, synaptosome. Note=Mainly localized to the plasma membrane.

Disease Associations

Tissue Specificity

Expressed in non-neuronal tissues.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 45 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	17 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	45 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006887	exocytosis
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport

Cellular Component

GO:0005634	nucleus
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0030054	cell junction
GO:0031410	cytoplasmic vesicle
GO:0042581	specific granule
GO:0042582	azurophil granule
GO:0043005	neuron projection
GO:0045202	synapse