InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: USP31

Summary

InnateDB Protein

IDBP-20159.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

USP31

Protein Name

ubiquitin specific peptidase 31

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000219689

InnateDB Gene

IDBG-20157 (USP31)

Protein Structure

UniProt Annotation

Function

May recognize and hydrolyze the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly- ubiquitin precursors as well as that of ubiquitinated proteins (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Widely expressed. {ECO:0000269PubMed:14715245}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004843	ubiquitin-specific protease activity
GO:0036459	ubiquitinyl hydrolase activity

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0016579	protein deubiquitination

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR028889 Ubiquitin carboxyl-terminal hydrolase-like domain
IPR029071 Ubiquitin-related domain

PFAM

PF00443

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q70CQ4

PhosphoSite