InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Glb1

Summary

InnateDB Protein

IDBP-203448.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Glb1

Protein Name

galactosidase, beta 1

Synonyms

AW125515; Bge; Bgl; Bgl-e; Bgl-s; Bgl-t; Bgs; Bgt; C130097A14Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000055803

InnateDB Gene

IDBG-203446 (Glb1)

Protein Structure

UniProt Annotation

Function

Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.

Subcellular Localization

Lysosome.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004565	beta-galactosidase activity
GO:0005515	protein binding
GO:0016936	galactoside binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0019388	galactose catabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0005764	lysosome
GO:0005794	Golgi apparatus
GO:0009341	beta-galactosidase complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:88151

InterPro

IPR001944 Glycoside hydrolase, family 35
IPR008979 Galactose-binding domain-like
IPR013529 Glycoside hydrolase, family 42, N-terminal
IPR017853 Glycoside hydrolase, superfamily

PFAM

PF01301
PF02449

PRINTS

PR00742

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P23780